Clarity Research Laboratory team is trained to take any kind of challenges in synthetic organic chemistry involving various types of chemistry viz heterocyclic, asymmetric, enzymatic and multi-step synthesis to deliver compounds to customer needs.
The Knowledge, experience and infrastructure at Clarity Research laboratory is comprised to carry out any custom synthesis for customer and collaborative medicinal chemistry programs needs.
Clarity Research laboratory, offers medicinal chemistry services with extensive synthetic and medicinal chemistry capabilities.
Clarity research laboratory has comprehensive process R&D (PRD) and manufacturing capabilities to support the CMC campaigns of NCE programs.
We offer the following services
Small scale synthesis
- Small scale synthesis up to 1g
- Medium scale synthesis from 1g to 100g
- Stereoselective synthesis of chiral molecules
- Chemoenzymatic and resolution technique for chiral molecules.
- Metabolite synthesis.
- Reference compound and scaffold synthesis.
Custom synthesis
- Flexible synthetic scale from milligrams to kilogram
- Final compound synthesis ranging from 100g to 2000g in non-GMP kilo laboratory.
- Synthesis of intermediates to support on-going medicinal chemistry programs.
- Final product/intermediates well characterized using the analytical facility (NMR, HPLC, or LC-MS).
Process Research & Development (PR&D) and Manufacturing:
- Route Scouting
- Process Design and Optimization
- Development and standardization of synthetic steps considering scalable manufacturing needs.
- Synthetic demonstration
- Scale up Manufacturing
- Transfer of process technology to pilot plant for advanced molecule.
Research Chemistry Services
- Contract Research and Development in synthetic organic chemistry.
- Synthesis of Focused Libraries & Analogues.
- Synthesis of Reference Standards & Metabolites.
- Synthesis of intermediates & catalog compounds.
Development Services
- Route design and optimization
- Scale –up of multi-step procedures up to Kg quantities
- Process Development & Optimization
- Process research, scale up and preparation of impurities.
- Synthesis of advanced intermediates.
- Multi step Synthesis
- Process development and scale up, large scale column chromatography separation and high vacuum distillation.